Characterization of p53 gene mutations in basal-cell carcinomas: comparison between sun-exposed and less-exposed skin areas.

doi:10.1002/(SICI)1097-0215(19960315)65:6<778::AID-IJC12>3.0.CO;2-0

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Article

Characterization of p53 gene mutations in basal-cell carcinomas: comparison between sun-exposed and less-exposed skin areas.

International journal of cancer - 15 Mar 1996

Matsumura Y, Nishigori C, Yagi T, Imamura S, Takebe H

Abstract excerpt

Mutations in the p53 gene in 32 basal-cell carcinomas (BCC) developed in Japanese patients were identified by the polymerase chain reaction and single-strand-conformation polymorphism analysis, followed by sequencing the DNA. Among 16 BCC developed in continuously sun-exposed areas, 6 tumors show...

Topics

Aged
Aged, 80 and over
Base Sequence
Carcinoma, Basal Cell
Female
Genes, p53
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation
Neoplasms, Radiation-Induced
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Skin
Skin Neoplasms
Sunlight

Source

Open in PubMed

Identifiers

PMID: 8631591
DOI: 10.1002/(SICI)1097-0215(19960315)65:6<778::AID-IJC12>3.0.CO;2-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8631591-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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