Article
A transforming MET mutation discovered in non-small cell lung cancer using microarray-based resequencing.
Cancer letters - 8 Aug 2006
Tengs Torstein, Lee Jeff C, Paez J Guillermo, Zhao Xiaojun, LaFramboise Thomas, Giannoukos Georgia, Thomas Roman K
Abstract excerpt
We have designed resequencing microarrays to test the performance of this platform when interrogating a large number of exons (164 total) from genes associated with cancer. To evaluate false positive and negative rates, dideoxy sequencing was done for 335,420 bases interrogated by the arrays. From the array data, calls could be made for approximately 97.5% of the bases, and false positive rates were very low with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
