Article
Analysis of MET kinase domain rearrangement in NSCLC.
Lung cancer (Amsterdam, Netherlands) - 1 Jul 2020
Zhuo Minglei, Liang Zhen, Yi Yuting, Wu Nan, Yang Xue, Zhong Jia, Chen Xiaohan, Huang Yi, Yu Zicheng, Liu Chang, Zeng Xiaoling, Gu Wenguang, Zhao Jun
Abstract excerpt
OBJECTIVES: Many MET rearrangements have been identified in various tumor types. However, the frequencies and characteristics of MET rearrangements are not well defined in non-small-cell lung cancer (NSCLC). We sought to illustrate the distribution of MET kinase domain rearrangements (KDREs) in NSCLC, and to uncover novel targets for further drug development in these patients. MATERIALS AND METHODS: Targeted...
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