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Overview of Molecular Detection Technologies for MET in Lung Cancer

26 May 2023

Abstract excerpt

MET tyrosine kinase receptor pathway activation has become an important actionable target in solid tumors. Aberrations in the MET proto-oncogene, including MET overexpression, the activation of MET mutations, MET mutations that lead to MET exon 14 skipping, MET gene amplifications, and MET fusions, are known to be primary and secondary oncogenic drivers in cancer; these aberrations have evolved as predictive...

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PMID: 37296895
DOI: 10.3390/cancers15112932

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