Article
MiRNAs associated polymorphisms in the 3'UTR of MET promote the risk of non-small cell lung cancer.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2015
Zhu Xiaojue, Fu Changqing, Zhang Lihua, Xu Guoxing, Wang Shusheng
Abstract excerpt
BACKGROUND/AIMS: MET can act as an oncogene and its signaling server has essential roles in regulating tumorigenesis. Polymorphisms in MET have been reported to be associated with poor prognosis in human cancer, but an association with the risk of human non-small-cell lung cancer (NSCLC) has not been found so far. In this study rs41281081 and rs76322625, located in the 3'UTR of MET, were selected to evaluate...
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