Article
Detection of MET gene somatic mutations in hepatocellular carcinoma of Egyptian patients using next-generation sequencing.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jun 2023
Ahmed Ehab, El-Dien A Nour, Sabet Salwa, Khalifa Mohamed, El Hamshary Manal
Abstract excerpt
INTRODUCTION: Hepatocellular carcinoma (HCC) is the sixth most common type of cancer worldwide and fourth in Egypt. Liquid biopsy is important to get cell-tumour DNA (ctDNA), for subsequent utilisation as a biomarker for cancer diagnosis, prognosis, and treatment. In clinical oncology, ctDNA analysis is utilised in cancer screening. METHODS: The collected 48 blood samples from HCC patients were classified...
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