Article
Performance of amplified DNA in an Illumina GoldenGate BeadArray assay.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2008
Cunningham Julie M, Sellers Thomas A, Schildkraut Joellen M, Fredericksen Zachary S, Vierkant Robert A, Kelemen Linda E, Gadre Madhura, Phelan Catherine M, Huang Yifan, Meyer Jeffrey G, Pankratz V Shane, Goode Ellen L
Abstract excerpt
Whole genome amplification (WGA) offers a means to enrich DNA quantities for epidemiologic studies. We used an ovarian cancer study of 1,536 single nucleotide polymorphisms (SNPs) and 2,368 samples to assess performance of multiple displacement amplification (MDA) WGA using an Illumina GoldenGate BeadArray. Initial screening revealed successful genotyping for 93.4% of WGA samples and 99.3% of genomic samples, and...
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