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Article

Genetic variation in IGFBP2 and IGFBP5 is associated with breast cancer in populations of African descent.

Human genetics - 1 Apr 2008

Garner Chad P, Ding Yuan C, John Esther M, Ingles Sue A, Olopade Olufunmilayo I, Huo Dezheng, Adebamowo Clement, Ogundiran Temidayo, Neuhausen Susan L

Abstract excerpt

The insulin-like growth factor (IGF) signaling pathway is thought to play a major role in the etiology of breast cancer. Although incidence rates of breast cancer overall are lower in African Americans than in Caucasians, African-American women have a higher incidence under age 40 years, are diagnosed with more advanced disease, and have poorer prognosis. We investigated the association of breast cancer and...

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Source

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Identifiers

PMID: 18210156
DOI: 10.1007/s00439-008-0468-x
PMCID: PMC4406274

Genes

IGFBP2
IGFBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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