Article
Positive associations between single nucleotide polymorphisms in the IGF2 gene region and body mass index in adult males.
Human molecular genetics - 1 Jul 2001
Gaunt T R, Cooper J A, Miller G J, Day I N, O'Dell S D
Abstract excerpt
We previously demonstrated an association between the insulin-like growth factor 2 (IGF2) gene 3'-untranslated region (3'-UTR) ApaI polymorphism and body mass index (BMI) in over 2500 middle-aged Caucasoid males. In the same cohort, we have now tested association with 11 more markers, including seven novel single nucleotide polymorphisms (SNPs), spanning >30 kb across the IGF2 gene. Three SNPs showed significant...
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