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Article

A comprehensive in silico analysis of the functional and structural impact of SNPs in the IGF1R gene.

Journal of biomedicine & biotechnology - 1 Jan 2010

de Alencar S A, Lopes Julio C D

Abstract excerpt

Insulin-like growth factor 1 receptor (IGF1R) acts as a critical mediator of cell proliferation and survival. Many single nucleotide polymorphisms (SNPs) found in the IGF1R gene have been associated with various diseases, including both breast and prostate cancer. The genetics of these diseases could be better understood by knowing the functions of these SNPs. In this study, we performed a comprehensive analysis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20625407
DOI: 10.1155/2010/715139
PMCID: PMC2896858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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