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Increased levels of CSF phosphorylated tau in apolipoprotein E epsilon4 carriers with mild cognitive impairment.

Neuroscience letters - 31 Dec 2005

Buerger Katharina, Teipel Stefan J, Zinkowski Raymond, Sunderland Trey, Andreasen Niels, Blennow Kaj, Ewers Michael, DeBernardis John, Shen Yong, Kerkman Daniel, Du Yansheng, Hampel Harald

Abstract excerpt

We investigated the correlation between the apolipoprotein E varepsilon4 allele (apoE epsilon4) carrier status, a major risk factor of Alzheimer's disease (AD), and levels of tau protein phosphorylated at threonine 231 (P-tau(231P)) in cerebrospinal fluid (CSF) in predementia and clinical stages of AD and healthy controls (HC). Thirty-one subjects with mild cognitive impairment (MCI) who had converted to AD...

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PMID: 16165272
DOI: 10.1016/j.neulet.2005.08.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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