Article
Increasing cerebrospinal fluid tau levels in a subgroup of Alzheimer patients with apolipoprotein E allele epsilon 4 during 14 months follow-up.
Neuroscience letters - 23 Aug 1996
Blomberg M, Jensen M, Basun H, Lannfelt L, Wahlund L O
Abstract excerpt
The concentration of tau protein is elevated in the cerebrospinal fluid (CSF) in Alzheimer's disease (AD), suggesting that CSF tau may be a useful biochemical diagnostic marker for this disorder. We investigated CSF tau concentrations on two occasions in AD (n = 18), mild cognitive impairment (MC...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Cognition Disorders
- DNA
- Dementia
- Disease Progression
- Enzyme-Linked Immunosorbent Assay
- Female
- Follow-Up Studies
- Genotype
- Humans
- Longitudinal Studies
- Male
- Middle Aged