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Article

Common human Toll-like receptor 9 polymorphisms and haplotypes: association with atopy and functional relevance.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Sept 2005

Berghöfer B, Frommer T, König I R, Ziegler A, Chakraborty T, Bein G, Hackstein H

Abstract excerpt

BACKGROUND: Toll-like receptor 9 (TLR9) is a pattern-recognition receptor that detects unmethylated CpG motifs prevalent in bacterial and viral DNA. TLR9 stimulation is a key event after bacterial infection, triggering innate immunity and T-helper type 1 skewed adaptive immunity. Synthetic CpG-oligodeoxynucleotides (CpG-ODNs) represent a promising and novel class of immune adjuvants for allergy treatment,...

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Source

Identifiers

PMID: 16164440
DOI: 10.1111/j.1365-2222.2005.02325.x

Genes

TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Common human Toll-like receptor 9 polymorphisms and haplotypes: association with atopy and functional relevance.PMID 16164440Read ↗

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