Article
[Association of single nucleotide polymorphisms in the promoter region of the TLR9 gene with childhood atopic asthma].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Apr 2011
QIAN Xu-bo, WU Ying, CAO Shu-yan, CAI Xiao-hong, YU Chen-yi, XUAN Miao-yan, CAO Shun-shun, LI Xiu-cui
Abstract excerpt
OBJECTIVE: To investigate the distribution characteristics of the single nucleotide polymorphisms (SNPs) in the promoter region of the toll-like receptor 9 gene (TLR9) in Chinese Han children from Zhejiang province, and their associations with asthma susceptibility and phenotypes. METHODS: A case-control study was conducted. A total of 312 asthmatic children aged between 1.9 and 11.6 and 339 age matched healthy...
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