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Article

Mutational analysis of human BAFF receptor TNFRSF13C (BAFF-R) in patients with common variable immunodeficiency.

Journal of clinical immunology - 1 Sept 2005

Losi Claretta Gioia, Silini Antonietta, Fiorini Claudia, Soresina Annarosa, Meini Antonella, Ferrari Simona, Notarangelo Luigi D, Lougaris Vassilios, Plebani Alessandro

Abstract excerpt

BAFF receptor (BAFF-R/BR3/TNFRSF13C) is a recently identified molecule that specifically binds BLyS, a protein belonging to the tumor necrosis factor (TNF) family, and is involved in survival and maturation of B cells. Recent studies have demonstrated that mice defective in BAFF-R gene exhibit an altered profile of the B cell pool, a phenotype observed in BLyS knockout mice as well. These features suggest that...

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PMID: 16160919
DOI: 10.1007/s10875-005-5637-2

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutational analysis of human BAFF receptor TNFRSF13C (BAFF-R) in patients with common variable immunodeficiency.PMID 16160919Read ↗

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