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Article

Sequence analysis of TNFRSF13b, encoding TACI, in patients with systemic lupus erythematosus.

Journal of clinical immunology - 1 Jul 2007

Salzer Ulrich, Birmelin Jennifer, Bacchelli Chiara, Witte Torsten, Buchegger-Podbielski Ulrike, Buckridge Sylvie, Rzepka Rita, Gaspar H Bobby, Thrasher Adrian J, Schmidt Reinhold E, Melchers Inga, Grimbacher Bodo

Abstract excerpt

B cell activating factor belonging to the TNF family (BAFF) and a proliferation inducing ligand (APRIL), and their receptors BAFF receptor (BAFFR), B cell maturation antigen (BCMA), and transmembrane activator and CAML interactor (TACI) are involved in the regulation of B cell homeostasis and differentiation. BAFF overexpression leads to systemic lupus erythematosus (SLE) in mice and elevated BAFF levels have...

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Identifiers

PMID: 17464555
DOI: 10.1007/s10875-007-9094-y

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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