Article
Chromosome-wise dissection of the genome of the extremely big mouse line DU6i.
Genetics - 1 Jan 2006
Bevova Marianna R, Aulchenko Yurii S, Aksu Soner, Renne Ulla, Brockmann Gudrun A
Abstract excerpt
The extreme high-body-weight-selected mouse line DU6i is a polygenic model for growth research, harboring many small-effect QTL. We dissected the genome of this line into 19 autosomes and the Y chromosome by the construction of a new panel of chromosome substitution strains (CSS). The DU6i chromosomes were transferred to a DBA/2 mice genetic background by marker-assisted recurrent backcrossing. Mitochondria and...
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