Article
Species-dependent expression patterns of DNA methyltransferase genes in mammalian oocytes and preimplantation embryos
12 Sept 2005
Abstract excerpt
DNA methyltransferases (DNMTs) comprise a family of proteins involved in the establishment and maintenance of DNA methylation patterns in the mammalian genome. DNA methylation involves the transfer of the methyl group of the coenzyme S-adenosyl-L-methionine to the 5 position of cytosine residues within CpG dinucleotides. DNA methylation is implicated in the control of imprinted genes expression, X chromosome...
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