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Active DNA demethylation in mammalian preimplantation embryos: new insights and new perspectives

23 Mar 2012

Abstract excerpt

DNA methylation and demethylation are crucial for modulating gene expression and regulating cell differentiation. Functions and mechanisms of DNA methylation/demethylation in mammalian embryos are still far from being understood clearly. In this review we firstly describe new insights into DNA demethylation mechanisms, and secondly introduce the differences in active DNA methylation patterns in zygotes and early...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22447119
DOI: 10.1093/molehr/gas014

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