Article
Y. enterocolitica translocated Yops impair stimulation of T-cells by antigen presenting cells.
Immunology letters - 15 Sept 2005
Kramer Uwe, Wiedig Carolin A
Abstract excerpt
As T helper cells play a crucial role in the defense of the mouse immune system against Yersinia enterocolitica, an effective subversion strategy for the pathogen would be the inhibition of T-cell activation. In this study, we investigated whether Y. enterocolitica impairs this process on the level of antigen presentation. For this purpose, we used T-cells to measure the antigen presentation capacity of dendritic...
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