Article
Evidence of genetic overlap of schizophrenia and bipolar disorder: linkage disequilibrium analysis of chromosome 18 in the Costa Rican population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Nov 2005
Walss-Bass Consuelo, Escamilla Michael A, Raventos Henriette, Montero A Patricia, Armas Regina, Dassori Albana, Contreras Salvador, Liu Wei, Medina Rolando, Balderas Teresa G, Levinson Douglas, Pereira Reynaldo, Pereira Mariana, Atmella Ivannia, Nesmith Lisa, Leach Robin, Almasy Laura
Abstract excerpt
The long-standing concept that schizophrenia (SC) and bipolar disorder (BP) represent two distinct illnesses has been recently challenged by findings of overlap of genetic susceptibility loci for these two diseases. We report here the results of a linkage disequilibrium (LD) analysis of chromosome 18 utilizing subjects with SC from the Central Valley of Costa Rica. Evidence of association (P < 0.05) was obtained...
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