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Article

Assessing the feasibility of linkage disequilibrium methods for mapping complex traits: an initial screen for bipolar disorder loci on chromosome 18.

American journal of human genetics - 1 Jun 1999

Escamilla M A, McInnes L A, Spesny M, Reus V I, Service S K, Shimayoshi N, Tyler D J, Silva S, Molina J, Gallegos A, Meza L, Cruz M L, Batki S, Vinogradov S, Neylan T, Nguyen J B, Fournier E, Araya C, Barondes S H, Leon P, Sandkuijl L A, Freimer N B

Abstract excerpt

Linkage disequilibrium (LD) analysis has been promoted as a method of mapping disease genes, particularly in isolated populations, but has not yet been used for genome-screening studies of complex disorders. We present results of a study to investigate the feasibility of LD methods for genome screening using a sample of individuals affected with severe bipolar mood disorder (BP-I), from an isolated population of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10330354
DOI: 10.1086/302400
PMCID: PMC1377910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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