Convergent linkage evidence from two Latin-American population isolates supports the presence of a susceptibility locus for bipolar disorder in 5q31-34.

doi:10.1093/hmg/ddl254

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Convergent linkage evidence from two Latin-American population isolates supports the presence of a susceptibility locus for bipolar disorder in 5q31-34.

Human molecular genetics - 1 Nov 2006

Herzberg Ibi, Jasinska Anna, García Jenny, Jawaheer Damini, Service Susan, Kremeyer Barbara, Duque Constanza, Parra María V, Vega Jorge, Ortiz Daniel, Carvajal Luis, Polanco Guadalupe, Restrepo Gabriel J, López Carlos, Palacio Carlos, Levinson Matthew, Aldana Ileana, Mathews Carol, Davanzo Pablo, Molina Julio, Fournier Eduardo, Bejarano Julio, Ramírez Magui, Ortiz Carmen Araya, Araya Xinia, Sabatti Chiara, Reus Victor, Macaya Gabriel, Bedoya Gabriel, Ospina Jorge, Freimer Nelson, Ruiz-Linares Andrés

Abstract excerpt

We performed a whole genome microsatellite marker scan in six multiplex families with bipolar (BP) mood disorder ascertained in Antioquia, a historically isolated population from North West Colombia. These families were characterized clinically using the approach employed in independent ongoing studies of BP in the closely related population of the Central Valley of Costa Rica. The most consistent linkage results...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 5

Share to Colombia

Share to Costa Rica

Share to Founder Effect

Share to Genome, Human

Share to Lod Score

Share to Statistics, Nonparametric

Source

Open in PubMed

Identifiers

PMID: 16984960
DOI: 10.1093/hmg/ddl254

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Convergent linkage evidence from two Latin-American population isolates supports the presence of a susceptibility locus for bipolar disorder in 5q31-34.PMID 16984960Read ↗

A narrow and highly significant linkage signal for severe bipolar disorder in the chromosome 5q33 region in Latin American pedigrees.Semantic proximity Read ↗

Genetic substrates of bipolar disorder risk in Latino families.Semantic proximity Read ↗

Fine-scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population.Semantic proximity Read ↗

Functional Genomics Studies of Psychiatric Disorders in Individuals of Latin American Populations: A Scoping Review.Semantic proximity Read ↗

A genome-wide linkage scan of bipolar disorder in Latino families identifies susceptibility loci at 8q24 and 14q32.Semantic proximity Read ↗

Genome-wide scan for linkage to schizophrenia in a Spanish-origin cohort from Costa Rica.Semantic proximity Read ↗

Results of a SNP genome screen in a large Costa Rican pedigree segregating for severe bipolar disorder.Semantic proximity Read ↗

Genetic mapping using haplotype and model-free linkage analysis supports previous evidence for a locus predisposing to severe bipolar disorder at 5q31-33.Semantic proximity Read ↗

Genomewide linkage disequilibrium mapping of severe bipolar disorder in a population isolate.Semantic proximity Read ↗

Diversity matters: opportunities in the study of the genetics of psychotic disorders in low- and middle-income countries in Latin AmericaSemantic proximity Read ↗

The conserved ASTN2/BRINP1 locus at 9q33.1-33.2 is associated with major psychiatric disorders in a large pedigree from Southern Spain.Semantic proximity Read ↗

Assessing the feasibility of linkage disequilibrium methods for mapping complex traits: an initial screen for bipolar disorder loci on chromosome 18.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.