Article
Distinct susceptibility of developing neurons to death following Bax overexpression in the chicken embryo.
Cell death and differentiation - 1 Mar 2006
Sato N, Sakuma C, Sato Y, Gould T W, Oppenheim R W, Yaginuma H
Abstract excerpt
Bax is a proapoptotic protein that is required for programmed cell death (PCD) of many neuronal populations. Here we show that, during an early period of retinal PCD and in naturally occurring sensory and motor neuron (MN) death in the spinal cord, Bax delivery results in enhanced death of these neural populations. In contrast, Bax overexpression fails to enhance an early phase of MN death that occurs in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
