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Article

Neuromuscular development in the absence of programmed cell death: phenotypic alteration of motoneurons and muscle.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Dec 2006

Buss Robert R, Gould Thomas W, Ma Jianjun, Vinsant Sharon, Prevette David, Winseck Adam, Toops Kimberly A, Hammarback James A, Smith Thomas L, Oppenheim Ronald W

Abstract excerpt

The widespread, massive loss of developing neurons in the central and peripheral nervous system of birds and mammals is generally considered to be an evolutionary adaptation. However, until recently, models for testing both the immediate and long-term consequences of preventing this normal cell loss have not been available. We have taken advantage of several methods for preventing neuronal death in vivo to ask...

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Identifiers

PMID: 17192424
DOI: 10.1523/JNEUROSCI.3528-06.2006
PMCID: PMC6674711

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Source receipt: pubmed, retrieved 7 Sept 2026.

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