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Article

Motor neuron degeneration is attenuated in bax-deficient neurons in vitro.

Journal of neuroscience research - 1 Mar 1999

Bar-Peled O, Knudson M, Korsmeyer S J, Rothstein J D

Abstract excerpt

Apoptosis plays a major role in motor neuron survival during developmental cell death, after axotomy, and in motor neuron diseases. Bax is the first member of the bcl-2 family shown to promote apoptosis. In the present study, we used the bax-deficient mouse model to determine the role of bax in m...

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Identifiers

PMID: 10082077
DOI: 10.1002/(SICI)1097-4547(19990301)55:5<542::AID-JNR2>3.0.CO;2-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10082077-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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