Article

Zebrafish live imaging reveals a surprisingly small percentage of spinal cord motor neurons die during early development

2024-01-27

Abstract excerpt

It is widely accepted that large numbers of neurons die during the early development of vertebrates; however, the tracking of this dying process in live animals remains challenging. Here, we generated sensor zebrafish achieving live imaging of motor neuron apoptosis at single- cell resolution. Using these sensor zebrafish, we observed for the first time that in an apoptotic motor neuron, caspase-3 activation occur...

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Literature Corpus work: 5e76adda-bc08-5d0b-be19-ae710b0b6b68
DOI: 10.1101/2024.01.26.577434

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