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Article

Release of Ca2+ from the endoplasmic reticulum contributes to Ca2+ signaling in Dictyostelium discoideum.

Eukaryotic cell - 1 Sept 2005

Wilczynska Zofia, Happle Kathrin, Müller-Taubenberger Annette, Schlatterer Christina, Malchow Dieter, Fisher Paul R

Abstract excerpt

Ca2+ responses to two chemoattractants, folate and cyclic AMP (cAMP), were assayed in Dictyostelium D. discoideum mutants deficient in one or both of two abundant Ca2+-binding proteins of the endoplasmic reticulum (ER), calreticulin and calnexin. Mutants deficient in either or both proteins exhibited enhanced cytosolic Ca2+ responses to both attractants. Not only were the mutant responses greater in amplitude,...

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Identifiers

PMID: 16151245
DOI: 10.1128/EC.4.9.1513-1525.2005
PMCID: PMC1214202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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