Article

Loss of Copine D Leads to Ras Activation in <i>Dictyostelium discoideum</i>

2026-04-11

Abstract excerpt

Copines are a family of calcium-dependent phospholipid-binding proteins conserved across numerous eukaryotes. The expression of multiple copine genes is dysregulated in several human cancers, yet their molecular functions remain poorly understood. We are investigating copine genes ( cpnA-cpnF ) in the amoeba Dictyostelium discoideum , a well-established model for studying conserved signaling pathways that regula...

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Literature Corpus work: 388318cb-666f-59a2-ab0b-8745c3a95f9f
DOI: 10.64898/2026.04.08.713907

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