Article
GrlJ, a Dictyostelium GABAB-like receptor with roles in post-aggregation development.
BMC developmental biology - 14 May 2007
Prabhu Yogikala, Müller Rolf, Anjard Christophe, Noegel Angelika A
Abstract excerpt
BACKGROUND: The G-protein-coupled receptor (GPCR) family represents the largest and most important group of targets for chemotherapeutics. They are extremely versatile receptors that transduce signals as diverse as biogenic amines, purins, odorants, ions and pheromones from the extracellular compartment to the interior via biochemical processes involving GTP-binding proteins. Until recently, the cyclic AMP...
Topics
- Animals
- Dictyostelium
- Gene Expression Regulation, Developmental
- Genes, Protozoan
- Green Fluorescent Proteins
- Mutation
- Phylogeny
- Receptors, GABA-B
- Spores, Protozoan