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Article

Role of Escherichia coli DNA polymerase I in conferring viability upon the dnaN159 mutant strain.

Journal of bacteriology - 1 Jul 2007

Maul Robert W, Sanders Laurie H, Lim James B, Benitez Rosemary, Sutton Mark D

Abstract excerpt

The Escherichia coli dnaN159 allele encodes a mutant form of the beta-sliding clamp (beta159) that is impaired for interaction with the replicative DNA polymerase (Pol), Pol III. In addition, strains bearing the dnaN159 allele require functional Pol I for viability. We have utilized a combination of genetic and biochemical approaches to characterize the role(s) played by Pol I in the dnaN159 strain. Our findings...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17449610
DOI: 10.1128/JB.00476-07
PMCID: PMC1913439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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