Article
Resistance to cisplatin in an E. coli B/r NalR mutant.
Mutation research - 1 Jun 1993
Bouayadi K, Villani G, Salles B
Abstract excerpt
The effects of various mutations in DNA-repair processes have been reported to either enhance or decrease bacterial sensitivity to cis-diamminedichloroplatinum(II) (cis-DDP). In the search for other mutations affecting bacterial sensitivity to this antitumor compound, we tested the E. coli B/r BS...
Topics
- Cisplatin
- DNA Repair
- DNA Topoisomerases, Type II
- DNA, Superhelical
- DNA-Binding Proteins
- Drug Resistance
- Escherichia coli
- Methylnitronitrosoguanidine
- Mitomycin
- Mutation
- Nalidixic Acid
- Plasmids
- Radiation Tolerance
- SOS Response, Genetics
- Ultraviolet Rays