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Article

Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization.

Cancer research - 1 Sept 2005

Jönsson Göran, Naylor Tara L, Vallon-Christersson Johan, Staaf Johan, Huang Jia, Ward M Renee, Greshock Joel D, Luts Lena, Olsson Håkan, Rahman Nazneen, Stratton Michael, Ringnér Markus, Borg Ake, Weber Barbara L

Abstract excerpt

Mutations in BRCA1 and BRCA2 account for a significant proportion of hereditary breast cancers. Earlier studies have shown that inherited and sporadic tumors progress along different somatic genetic pathways and that global gene expression profiles distinguish between these groups. To determine whether genomic profiles similarly discriminate among BRCA1, BRCA2, and sporadic tumors, we established DNA copy number...

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Identifiers

PMID: 16140926
DOI: 10.1158/0008-5472.CAN-05-0570

Genes

BRCA1
BRCA2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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