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Current concepts in breast cancer genomics: An evidence based review by the CGC breast cancer working group.

Cancer genetics - 1 Jun 2020

Geiersbach Katherine B, Chen Hui, Emmadi Rajyasree, Haskell Gloria T, Lu Xinyan, Liu Yajuan J, Swisshelm Karen

Abstract excerpt

BACKGROUND: Genomic abnormalities in breast cancer have been described according to diverse conceptual frameworks, including histologic subtypes, clinical molecular subtypes, intrinsic DNA, RNA, and epigenetic profiles, and activated molecular pathways. METHODS: The Cancer Genomics Consortium (CGC) Breast Cancer Workgroup performed an evidence based literature review to summarize current knowledge of clinically...

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PMID: 32087595
DOI: 10.1016/j.cancergen.2020.02.002

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