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Article

DNA methylation of genes linked with retinoid signaling in gastric carcinoma

30 Aug 2005

Abstract excerpt

BACKGROUND: Hypermethylation of CpG islands has been associated with silencing of various tumor suppressor genes, and the retinoid acid receptor beta (RARbeta), cellular retinol-binding protein 1 (CRBP1), and tazarotene-induced gene 1 (TIG1) genes have been associated with retinoic acid signaling. To the authors' knowledge, little is known regarding the involvement of these three genes in gastric carcinoma (GC)....

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Share to Epigenetics and DNA Methylation
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PMID: 16134180
DOI: 10.1002/cncr.21392

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