Article
Expression and mutation analysis of TIG1 (tazarotene-induced gene 1) in human gastric cancer.
Oncology research - 1 Jan 2009
Son Min Soo, Kang Min-Ju, Park Ho Chul, Chi Sung-Gil, Kim Yong Ho
Abstract excerpt
Tazarotene-induced gene 1 (TIG1) has been known to function as a cell adhesion molecule, which leads to better cell to cell contact and reduced proliferation. We investigated expression and mutation status of TIG1 in primary gastric tumors and cell lines to explore the candidacy of the gene as a tumor suppressor. A total of 172 gastric tissue specimes, including 80 primary adenocarcinomas, 12 benign tumors, and...
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