Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RRIG1 Mediates Effects of Retinoic Acid Receptor β2 on Tumor Cell Growth and Gene Expression through Binding to and Inhibition of RhoA

15 Jul 2006

Abstract excerpt

The expression of retinoic acid receptor beta2 (RAR-beta2) is frequently lost in various cancers and their premalignant lesions. However, the restoration of RAR-beta2 expression inhibits tumor cell growth and suppresses cancer development. To understand the molecular mechanisms responsible for this RAR-beta2-mediated antitumor activity, we did restriction fragment differential display-PCR and cloned a novel...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Estrogen and related hormone effects
Share to Retinoids in leukemia and cellular processes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16849557
DOI: 10.1158/0008-5472.can-06-0812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RRIG1 Mediates Effects of Retinoic Acid Receptor β2 on Tumor Cell Growth and Gene Expression through Binding to and Inhibition of RhoAPMID 16849557Read ↗

RAI2 acts as a tumor suppressor with functional significance in gastric cancerSemantic proximity Read ↗

Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype.Semantic proximity Read ↗

Comprehensive expression analysis of retinoic acid receptors and retinoid X receptors in non-small cell lung cancer: implications for tumor development and prognosisSemantic proximity Read ↗

Retinoic acid receptor gamma is required for proliferation of pancreatic cancer cellsSemantic proximity Read ↗

Downregulation of Fibronectin 1 Attenuates ATRA-induced Inhibition of Cell Migration and Invasion in Neuroblastoma CellsSemantic proximity Read ↗

Enhanced expression of retinoic acid receptor alpha (RARA) induces epithelial‐to‐mesenchymal transition and disruption of mammary acinar structuresSemantic proximity Read ↗

RERG Is a Novel ras-related, Estrogen-regulated and Growth-inhibitory Gene in Breast CancerSemantic proximity Read ↗

Blockage of retinoic acid signaling via RARγ suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phaseSemantic proximity Read ↗

RORβ suppresses the stemness of gastric cancer cells by downregulating the activity of the Wnt signaling pathwaySemantic proximity Read ↗

The Role and Clinical Implications of the Retinoblastoma (RB)-E2F Pathway in Gastric CancerSemantic proximity Read ↗

Identification of receptor-selective retinoids that are potent inhibitors of the growth of human head and neck squamous cell carcinoma cells.Semantic proximity Read ↗

Rac GTPase activating protein 1 promotes gallbladder cancer via binding DNA ligase 3 to reduce apoptosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.