Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma.

International journal of cancer - 10 Jun 2004

Oshimo Yasuhiro, Oue Naohide, Mitani Yoshitsugu, Nakayama Hirofumi, Kitadai Yasuhiko, Yoshida Kazuhiro, Chayama Kazuaki, Yasui Wataru

Abstract excerpt

The retinoblastoma protein-interacting zinc finger gene, RIZ1 (GenBank accession number U17838), is involved in chromatin-mediated gene expression and is also a target for frameshift mutation in microsatellite-unstable cancers. Methylation of the RIZ1 promoter CpG island has been shown to be a co...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to DNA-Binding Proteins
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Histone-Lysine N-Methyltransferase

Share to Nuclear Proteins

Share to Promoter Regions, Genetic

Share to Stomach Neoplasms

Source

Identifiers

PMID: 15069684
DOI: 10.1002/ijc.20090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15069684-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma.PMID 15069684Read ↗

Biallelic inactivation of the RIZ1 gene in human gastric cancer.Semantic proximity Read ↗

Hyper-methylation of RIZ1 tumor suppressor gene is involved in the early tumorigenesis of hepatocellular carcinoma.Semantic proximity Read ↗

Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily.Semantic proximity Read ↗

Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma.Semantic proximity Read ↗

RIZ, the retinoblastoma protein interacting zinc finger gene, is mutated in genetically unstable cancers of the pancreas, stomach, and colorectum.Semantic proximity Read ↗

Frequent frameshift mutations of RIZ in sporadic gastrointestinal and endometrial carcinomas with microsatellite instability.Semantic proximity Read ↗

Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype.Semantic proximity Read ↗

Mapping of a minimal deleted region in human hepatocellular carcinoma to 1p36.13-p36.23 and mutational analysis of the RIZ (PRDM2) gene localized to the region.Semantic proximity Read ↗

Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesisSemantic proximity Read ↗

Genetic polymorphisms in the Rb-binding zinc finger gene RIZ and the risk of lung cancer.Semantic proximity Read ↗

MGMT gene silencing by promoter hypermethylation in gastric cancer in a high incidence areaSemantic proximity Read ↗

The retinoblastoma protein-interacting zinc finger gene RIZ in 1p36-linked cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.