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Article

High frequencies of functionally impaired cytokeratin 18-specific CD8+ T cells in healthy HLA-A2+ donors.

European journal of immunology - 1 Oct 2005

Walter Steffen, Bioley Gilles, Bühring Hans-Jörg, Koch Sven, Wernet Dorothee, Zippelius Alfred, Pawelec Graham, Romero Pedro, Stevanović Stefan, Rammensee Hans-Georg, Gouttefangeas Cécile

Abstract excerpt

Combining cell surface phenotyping with functional analysis, human CD8+ T cells have been divided into several subsets which are being studied extensively in diverse physiological situations, such as viral infection, cancer and ageing. In particular, so-called terminally differentiated effector cells possess a CD45RA+ CCR7- CD27- CD28- phenotype, contain perforin and, in different models, have been shown to exert...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16134083
DOI: 10.1002/eji.200526207

Genes

CCR7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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