NK phenotypic markers and IL2 response in NK cells from elderly people.

doi:10.1016/s0531-5565(98)00076-x

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Article

NK phenotypic markers and IL2 response in NK cells from elderly people.

Experimental gerontology - 1 Apr 1999

Borrego F, Alonso M C, Galiani M D, Carracedo J, Ramirez R, Ostos B, Peña J, Solana R

Abstract excerpt

Immunosenescence is a process that primarily affects the T cell compartment of the immune system, although age-associated immunological alterations have also been demonstrated in the NK cell phenotype and function. A significant expansion in the number of NK cells is found in aging. The NK cytotoxic capacity of total peripheral blood lymphocytes is also well preserved, not only in healthy elderly people but also...

Topics

Adult
Aged
Aged, 80 and over
Aging
Biomarkers
CD3 Complex
CD56 Antigen
Calcium
Cell Division
Cytotoxicity, Immunologic
Humans
In Vitro Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-2

Killer Cells, Natural

Lymphocyte Activation

Phenotype

Signal Transduction

Tumor Necrosis Factor-alpha

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Open in PubMed

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PMID: 10363791
DOI: 10.1016/s0531-5565(98)00076-x

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