Article
Lipoprotein lipase gene is linked and associated with hypertension in Taiwan young-onset hypertension genetic study.
Journal of biomedical science - 1 Jan 2005
Chen Pei, Jou Yuh-Shan, Fann Cathy S J, Chen Jaw-Wen, Wu Sheng-Yeu, Pan Wen-Harn
Abstract excerpt
Hypertriglyceridemia has been extensively associated with hypertension. However, the mechanism behind it is poorly understood. A positive linkage signal between Lipoprotein lipase (LPL) and young-onset hypertension has been identified by us as the strongest among 18 candidate genes. Here we report our fine mapping works with seven microsatellite markers flanking LPL, sequencing results for its promoter and exons,...
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