Article
Variation near the region of the lipoprotein lipase gene and hypertension or blood pressure levels in Chinese.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jun 2003
Yang Wenjie, Huang Jianfeng, Ge Dongliang, Yao Cailiang, Duan Xiufang, Gan Wenqi, Huang Guangyong, Zhao Jiangong, Hui Rutai, Shen Yan, Qiang Boqin, Gu Dongfeng
Abstract excerpt
Essential hypertension (EH) is a common late-onset disease that exhibits complex genetic heterogeneity. Human lipoprotein lipase (LPL) is a rate-limiting enzyme that regulates the catabolism of triglycerides (TG) and chylomicrons (CM). Since dyslipidemia is a common finding in hypertensive patients, the LPL gene is a logical candidate gene that could contribute to the development of hypertension. Using linkage...
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