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Article

Lipoprotein lipase variants associated with an endophenotype of hypertension: hypertension combined with elevated triglycerides.

Human mutation - 1 Jan 2009

Chen Pei, Jou Yuh-Shan, Fann Cathy S J, Chen Jaw-Wen, Chung Chia-Min, Lin Chin-Yu, Wu Sheng-Yeu, Kang Mei-Jyh, Chen Ying-Chuang, Jong Yuh-Shiun, Lo Huey-Ming, Kang Chih-Sen, Chen Chien-Chung, Chang Huan-Cheng, Huang Nai-Kuei, Wu Yi-Lin, Pan Wen-Harn

Abstract excerpt

Previously, we observed that young-onset hypertension was independently associated with elevated plasma triglyceride(s) (TG) levels to a greater extent than other metabolic risk factors. Thus, focusing on the endophenotype--hypertension combined with elevated TG--we designed a family-based haplotype association study to explore its genetic connection with novel genetic variants of lipoprotein lipase gene (LPL),...

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Identifiers

PMID: 18649389
DOI: 10.1002/humu.20812

Genes

LPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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