Article
Linkage analysis with candidate genes: the Taiwan young-onset hypertension genetic study.
Human genetics - 1 Sept 2000
Pan W H, Chen J W, Fann C, Jou Y S, Wu S Y
Abstract excerpt
A genetic linkage study of young-onset hypertension was performed on data from 59 nucleus families of Han Chinese residing in Taiwan. Thirty seven microsatellite markers near 18 hypertension candidate genes were genotyped. In a nonparametric identity-by-descent sibpair analysis, a positive linkage signal (defined as P<0.05) was found for four microsatellite markers, viz., D1S1612 (P=0.0162), D1S547 (P=0.0263),...
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