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Article

Lipoprotein lipase gene is in linkage with blood pressure phenotypes in Chinese pedigrees.

Human genetics - 1 Jun 2004

Yang Wenjie, Huang Jianfeng, Ge Dongliang, Yao Cailiang, Duan Xiufang, Shen Yan, Qiang Boqin, Gu Dongfeng

Abstract excerpt

To elucidate the mechanism of lipid metabolism in the genesis of essential hypertension (EH), we linked blood pressure (BP) phenotypes with the lipoprotein lipase (LPL) gene. Variance component and sib-pair linkage models were used to test the relationship of the polymorphisms in the LPL gene region and EH in 148 Chinese hypertensive families. Linkage evidence with systolic BP (SBP) and diastolic BP (DBP) was...

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Identifiers

PMID: 15127290
DOI: 10.1007/s00439-004-1108-8

Genes

LPL
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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