Article
Lipoprotein lipase: genetics, lipid uptake, and regulation.
Journal of lipid research - 1 Dec 2002
Merkel Martin, Eckel Robert H, Goldberg Ira J
Abstract excerpt
Lipoprotein lipase (LPL) regulates the plasma levels of triglyceride and HDL. Three aspects are reviewed. 1) Clinical implications of human LPL gene variations: common mutations and their effects on plasma lipids and coronary heart disease are discussed. 2) LPL actions in the nervous system, liver, and heart: the discussion focuses on LPL and tissue lipid uptake. 3) LPL gene regulation: the LPL promoter and its...
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