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Article

2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research.

Journal of cardiovascular translational research - 1 Jun 2015

Flister Michael J, Prokop Jeremy W, Lazar Jozef, Shimoyama Mary, Dwinell Melinda, Geurts Aron

Abstract excerpt

The rat has long been a key physiological model for cardiovascular research, most of the inbred strains having been previously selected for susceptibility or resistance to various cardiovascular diseases (CVD). These CVD rat models offer a physiologically relevant background on which candidates of human CVD can be tested in a more clinically translatable experimental setting. However, a diverse toolbox for...

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Identifiers

PMID: 25920443
DOI: 10.1007/s12265-015-9626-4
PMCID: PMC4475456

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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