Hypertension, kidney, and transgenics: a fresh perspective.

doi:10.1152/physrev.00016.2005

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Article

Hypertension, kidney, and transgenics: a fresh perspective.

Physiological reviews - 1 Apr 2006

Mullins Linda J, Bailey Matthew A, Mullins John J

Abstract excerpt

In this review, we outline the application and contribution of transgenic technology to establishing the genetic basis of blood pressure regulation and its dysfunction. Apart from a small number of examples where high blood pressure is the result of single gene mutation, essential hypertension is the sum of interactions between multiple environmental and genetic factors. Candidate genes can be identified by a...

Topics

Animals
Blood Pressure
Genetic Predisposition to Disease
Genetic Techniques
Humans
Hypertension
Kidney
Risk Factors
Sodium

Source

Open in PubMed

Identifiers

PMID: 16601272
DOI: 10.1152/physrev.00016.2005

Provenance

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