Article
Tumour necrosis is an independent prognostic marker in non-small cell lung cancer: correlation with biological variables.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2002
Swinson Daniel E B, Jones J Louise, Richardson Donna, Cox Giles, Edwards John G, O'Byrne Kenneth J
Abstract excerpt
BACKGROUND: Tumour necrosis (TN) is recognized to be a consequence of chronic cellular hypoxia. TN and hypoxia correlate with poor prognosis in solid tumours. METHODS: In a retrospective study the prognostic implications of the extent of TN was evaluated in non-small cell lung cancer (NSCLC) and correlated with clinicopathological variables and expression of epidermal growth factor receptor, Bcl-2, p53 and matrix...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.