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Article

The cAMP signalling pathway activates CREB through PKA, p38 and MSK1 in NIH 3T3 cells.

Cellular signalling - 1 Nov 2005

Delghandi Marit Pedersen, Johannessen Mona, Moens Ugo

Abstract excerpt

Cyclic adenosine 3',5'-monophosphate (cAMP) was originally shown to induce gene transcription through activation of cAMP-dependent protein kinase (PKA), and subsequent phosphorylation of the transcription factor cAMP response element-binding protein, CREB, at serine-133. However, elevated cAMP levels may activate multiple signalling pathways with protein kinases that can phosphorylate CREB at serine-133. We...

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Source

Identifiers

PMID: 16125054
DOI: 10.1016/j.cellsig.2005.02.003

Genes

MAPKAPK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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